J01CF02 - Cloxacillin |
Not Porphyrinogenic |
NP |
Rationale
Metabolised only to a limited extent. Two references state non-porphyrinogenicity.
Chemical description
Penicillinase stable penicillin used parenterally (up to 2g x 3) in staphylococcal infections mainly eliminated in unchanged form by renal excretion. No clear data pointing to CYP-interaction. Half life in blood is 30 minutes, 30-50% of the dose being excreted within 6 hours.
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References
| # | Citation details | PubMed ID |
|---|---|---|
| Porphyria Drug Lists | ||
| 1. | Australian List
Australian Porphyria Association No longer maintained
|
|
| 2. | South African List
Porphyria South Africa No longer maintained
|
|
Tradenames
Dry Clox 
Cloxin 
Cloxacilline · Orbenine 
Anaclosil · Cloxacilina · Orbenin 
Cloxacillin 
Cloxacillin · Ekvacillin · Extempore J01CF02 Kloxacillin · Kloxacillin 
Cloxacillin 
Cloxacillin · Syntarpen 
Cloxacap · Cloxacillin · Oxacil 
Cloxacillin 
Cloxacillin 
Cloxacillin 
Cloxacillin 
Monoclox 
Anaclosil · Cloxacilina · Cloxacillin · Monoclox · Orbenin 
Orbenin 
Cloxacilline 
Cloxacilina 
Cloxacillin